DNA Binding Motif

						

			
Accessions: POU2F1_DLX2_1 (HumanTF2 1.0)

			
Names: POU2F1_DLX2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: tgAATATkcaTmCAcTAATTG
Weblogo: 
PSSM: P0      A      C      G      T
01    379    108    346    877      t
02    134     18    877    275      g
03    755    122      0      0      A
04    877      6     30     37      A
05      1      0      0    877      T
06    877      0      0      0      A
07     13      4     73    877      T
08      0      7    335    542      k
09    109    877     26    306      c
10    877     40    264    374      a
11     16     67     86    708      T
12    295    476     66     40      m
13      0    669     40    169      C
14    713     97     67      0      A
15      0    583    203     91      c
16      4    163      0    877      T
17    877    100      0     29      A
18    877     11    136      0      A
19     39     33     74    877      T
20    157     14     16    861      T
21     83      1    794     19      G
Type: Heterodimer
Binding TFs: DLX2_TF2 (Homeobox domain, Homeobox protein distal-less-like N terminal )
POU2F1_TF1 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
DLX2_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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