DNA Binding Motif

						

			
Accessions: ETV2_SOX15_2 (HumanTF2 1.0)

			
Names: ETV2_SOX15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: rsCGGAAryrsbyyAtTGT
Weblogo: 
PSSM: P0      A      C      G      T
01    314     78    356     63      r
02     54    415    256     70      s
03     71    671     40     36      C
04      0      0    671      2      G
05      4      5    671      0      G
06    671      0     21     10      A
07    671     21      0    132      A
08    176     80    399     16      r
09     15    218     68    370      y
10    180     81    243    167      r
11    114    171    277    109      s
12     16    260    213    182      b
13      9    316    161    185      y
14     81    424     78    246      y
15    503     16     50    168      A
16    101     68    203    671      t
17     27     51     54    671      T
18     59     13    671     89      G
19     90     47     40    671      T
Type: Heterodimer
Binding TFs: SOX15_TF2 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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