DNA Binding Motif

						

			
Accessions: 4nqa_HI (3D-footprint 20231221)

			
Names: Retinoic acid receptor RXR-alpha
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of liganded hRXR-alpha/hLXR-beta heterodimer on DNA
Length: 15
Consensus: GnCCCnnnGTnnCCC
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0     96      0      G
02     24     24     24     24      n
03      0     96      0      0      C
04     12     72      6      6      C
05      0     84      6      6      C
06     24     24     24     24      n
07     24     24     24     24      n
08     24     24     24     24      n
09      6      6     78      6      G
10      6      6      6     78      T
11     24     24     24     24      n
12     24     24     24     24      n
13      0     96      0      0      C
14      0     96      0      0      C
15      6     72      6     12      C
Type: Heterodimer
Binding TFs: 4nqa_H (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
4nqa_I (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
Binding Sites: 4nqa_L
4nqa_M
			
Publications: Lou X, Toresson G, Benod C, Suh J.H, Philips K.J, Webb P, Gustafsson J.A. Structure of the retinoid X receptor α-liver X receptor β (RXRα-LXRβ) heterodimer on DNA. Nature structural & molecular biology 21:277-81 (2014). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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