DNA Binding Motif

Accessions: MA0498.3 (JASPAR 2024)
Names: MEIS1
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HT-SELEX
Length: 5
Consensus: TGACA
Weblogo:
PSSM: P0 A C G T
01 8690 5575 3174 77159 T
02 0 1249 77159 0 G
03 77159 2903 672 0 A
04 0 77159 0 1155 C
05 77159 0 9263 3861 A
Type: Heterodimer
Binding TFs: O00470 (Homeobox domain, Homeobox KN domain)
O00470
Publications: Knoepfler P. S., Calvo K. R., Chen H., Antonarakis S. E., Kamps M. P. Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1. Proc. Natl. Acad. Sci. USA 94:14553-14558 (1997). [Pubmed]

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