DNA Binding Motif

						

			
Accessions: ETV2_CEBPD (HumanTF2 1.0), UN0510.1 (JASPAR 2024)

			
Names: ETV2_CEBPD, ETV2::CEBPD
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 17
Consensus: rsCGGAwrTTrCGyAAy
Weblogo: 
PSSM: P0      A      C      G      T
01    789    322    523    365      r
02    351    868    444     91      s
03    352   1312     90     26      C
04     39     21   1312     14      G
05     44     19   1312      8      G
06   1312     21     36     71      A
07    634    193     31    454      w
08    501    119    676     16      r
09      2      1      4   1312      T
10      3      5    177   1312      T
11    910      7   1312    164      r
12     66   1312     78    261      C
13    227    107   1312     64      G
14    246    677     12    635      y
15   1312    397     12     22      A
16   1312      2     19     11      A
17     98    509    273    431      y
Type: Heterodimer
Binding TFs: CEBPD_TF2 (bZIP transcription factor, Basic region leucine zipper)
ETV2_TF1 (Ets-domain)
Q3KNT2 (Ets-domain)
Q3KNT2
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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