DNA Binding Motif

Accessions: HOXB13_TBX3_1 (HumanTF2 1.0)
Names: HOXB13_TBX3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: cycrTAAwTcaCACst
Weblogo:
PSSM: P0 A C G T
01 33 141 48 27 c
02 16 86 22 125 y
03 53 131 15 50 c
04 149 0 100 28 r
05 0 6 10 249 T
06 249 1 17 59 A
07 249 5 1 0 A
08 249 33 2 106 w
09 32 35 11 249 T
10 66 249 78 24 c
11 249 0 82 72 a
12 0 249 7 5 C
13 249 0 55 11 A
14 9 249 3 0 C
15 13 125 66 44 s
16 49 42 17 141 t
Type: Heterodimer
Binding TFs: HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
TBX3_TF2 (T-box)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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