DNA Binding Motif

Accessions: TEAD4_ERG_1 (HumanTF2 1.0)
Names: TEAD4_ERG
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 12
Consensus: ACCGGAAATrCc
Weblogo:
PSSM: P0 A C G T
01 1649 129 307 108 A
02 217 1836 120 25 C
03 110 1956 0 6 C
04 38 6 1956 7 G
05 0 1 1956 0 G
06 1956 12 7 0 A
07 1956 33 0 0 A
08 1956 5 129 8 A
09 0 69 33 1956 T
10 853 18 1102 178 r
11 222 1956 307 56 C
12 337 1956 308 600 c
Type: Heterodimer
Binding TFs: ERG_TF1 / ERG_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
TEAD4_TF1 (TEA/ATTS domain family)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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