DNA Binding Motif

						

			
Accessions: FOXJ2_HOXB13_2_3_4 (HumanTF2 1.0)

			
Names: FOXJ2_HOXB13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: kTTwAykrymaACA
Weblogo: 
PSSM: P0      A      C      G      T
01    272     60    416    888      k
02      7     74     89    888      T
03     24      0     11    888      T
04    270     94     53    619      w
05    888      0      0    156      A
06     28    360     66    888      y
07    111     25    319    433      k
08    465     92    424     37      r
09    151    246    141    350      y
10    357    531      0     33      m
11    888    277     38    111      a
12    888      0     56    192      A
13     88    888     20    159      C
14    888    175    162     67      A
Type: Heterodimer
Binding TFs: HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
FOXJ2_TF1 (Fork head domain)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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