DNA Binding Motif

						

			
Accessions: ETV2_ONECUT2_2 (HumanTF2 1.0), UN0519.1 (JASPAR 2024)

			
Names: ETV2_ONECUT2, ETV2::ONECUT2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 18
Consensus: rATCrATaacCGGAAryg
Weblogo: 
PSSM: P0      A      C      G      T
01    857    208    508    117      r
02   1134     52    230     72      A
03      0      0      0   1364      T
04     16   1364      0     10      C
05    491     32    874     19      r
06   1364     19     61     99      A
07     27     25     13   1364      T
08    823     97    268    176      a
09    863    131    238    133      a
10    254    725    339     47      c
11    227   1364     43      0      C
12      1     19   1364      0      G
13      1      6   1364     16      G
14   1364     17      0     13      A
15   1364     98     16    309      A
16    438     47    926     28      r
17     94    576     79    788      y
18    325    185    642    213      g
Type: Heterodimer
Binding TFs: ONECUT2_TF2 (Homeobox domain, CUT domain)
ETV2_TF1 (Ets-domain)
ONECUT2_Full (Homeobox domain, CUT domain)
Q3KNT2 (Ets-domain)
Q3KNT2
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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