DNA Binding Motif

						

			
Accessions: MA0143.4 (JASPAR 2024)

			
Names: SOX2
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 11
Consensus: wwACAATGgww
Weblogo: 
PSSM: P0      A      C      G      T
01  29105  11041  21434  24174      w
02  30279  15154  17157  23164      w
03  83515    436    418   1385      A
04   1307  78356   1243   4848      C
05  81587   1205    550   2412      A
06  80825   1742   2002   1185      A
07   4815    732    930  79277      T
08   9926    800  73372   1656      G
09  14772   6264  54414  10304      g
10  28860  17158  17765  21971      w
11  28960  17475  15998  23321      w
Type: Heterodimer
Binding TFs: P48431 (HMG (high mobility group) box, Domain of unknown function (DUF1898), SOX transcription factor)
P48431
Binding Sites: MA0143.4.4
MA0143.4.1
MA0143.4.10
MA0143.4.11 / MA0143.4.7
MA0143.4.12 / MA0143.4.8
MA0143.4.13
MA0143.4.14
MA0143.4.15 / MA0143.4.9
MA0143.4.10 / MA0143.4.16
MA0143.4.17
MA0143.4.11 / MA0143.4.18
MA0143.4.12 / MA0143.4.19
MA0143.4.1 / MA0143.4.2
MA0143.4.13 / MA0143.4.20
MA0143.4.3
MA0143.4.2 / MA0143.4.5
MA0143.4.3 / MA0143.4.6
MA0143.4.4 / MA0143.4.7
MA0143.4.8
MA0143.4.5 / MA0143.4.9
MA0143.4.14
MA0143.4.15
MA0143.4.16
MA0143.4.17
MA0143.4.18
MA0143.4.19
MA0143.4.20
MA0143.4.6
			
Publications: Maruyama M., Ichisaka T., Nakagawa M., Yamanaka S. Differential roles for Sox15 and Sox2 in transcriptional control in mouse embryonic stem cells.. J. Biol. Chem. 280:24371-24379 (2005). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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