DNA Binding Motif

						

			
Accessions: TEAD4_ERG_2 (HumanTF2 1.0)

			
Names: TEAD4_ERG
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: aCCGGAArTrvawgrcATwCC
Weblogo: 
PSSM: P0      A      C      G      T
01    673    111    173     80      a
02    143    694    152     13      C
03    110    846      3      7      C
04      0     25    846      0      G
05      6      4    846      0      G
06    846     25      0     11      A
07    846     80      2     77      A
08    546     37    251     13      r
09     19    203      0    624      T
10    323     47    404     73      r
11    216    372    217     41      v
12    298    204    159    186      a
13    236    191    132    287      w
14    194    135    336    182      g
15    381     38    240    186      r
16    279    846    168      0      c
17    846      0      6      0      A
18      0      0     13    846      T
19    402      0     35    445      w
20    163    846     86     69      C
21    200    846      1     91      C
Type: Heterodimer
Binding TFs: ERG_TF1 / ERG_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
TEAD4_TF1 (TEA/ATTS domain family)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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