DNA Binding Motif

						

			
Accessions: MEIS1_ONECUT2 (HumanTF2 1.0)

			
Names: MEIS1_ONECUT2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: TGACAgawAATCrATr
Weblogo: 
PSSM: P0      A      C      G      T
01   2759   4570   1132  21020      T
02    703      0  24692    111      G
03  23606     22   2191    332      A
04    499  25028     66    428      C
05  22555     24   4631    314      A
06   1945   4378  22336   7063      g
07  10256   4560   5445   4896      a
08  13247    754    129  11809      w
09  21536   2891   1777   1968      A
10  23932   1092   3902    869      A
11    217    567    161  25033      T
12    203  24820     19    366      C
13   9378    263  15517    729      r
14  23535    188    281   2151      A
15   2178     87     97  24425      T
16  11199   3129  12082   5384      r
Type: Heterodimer
Binding TFs: MEIS1_TF1 (Homeobox domain, Homeobox KN domain)
ONECUT2_TF2 (Homeobox domain, CUT domain)
MEIS1_Crystal (Homeobox domain, Homeobox KN domain)
ONECUT2_Full (Homeobox domain, CUT domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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