DNA Binding Motif

						

			
Accessions: UP00085A_2 (UniPROBE 20160601)

			
Names: 31 kDa transforming protein, Dis-1, Dis1, PU.1, SFFV proviral integration 1, SFFV proviral integration 1 protein, Sfpi-1, Sfpi1, Spi-1, Spi1, Tcfpu1, Tfpu.1, Transcription factor PU.1
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 14
Consensus: maawttmvgGAAcc
Weblogo: 
PSSM: P0      A      C      G      T
01   0.26   0.40   0.12   0.22      m
02   0.41   0.21   0.18   0.21      a
03   0.66   0.05   0.15   0.14      a
04   0.48   0.06   0.03   0.43      w
05   0.22   0.09   0.02   0.67      t
06   0.21   0.11   0.12   0.56      t
07   0.31   0.36   0.16   0.17      m
08   0.31   0.32   0.29   0.07      v
09   0.22   0.06   0.66   0.05      g
10   0.12   0.08   0.73   0.07      G
11   0.73   0.04   0.10   0.14      A
12   0.73   0.11   0.04   0.13      A
13   0.22   0.54   0.12   0.12      c
14   0.22   0.48   0.12   0.19      c
Binding TFs: UP00085A (Ets-domain)
Binding Sites: AAACTTCC
AACTTCCC
AACTTCCG
AACTTCCT
ACTTCCCA
ACTTCCCC
ACTTCCCT
ACTTCCGC
ACTTCCGG
ACTTCCTC
AGCGGAAG
AGGAAGTA
AGTTCCCC
AGTTCCTC
ATGCGGAA
CACTTCCC
CTTCCGCA
GGAAGTAA
GGGAAGTA
TTCCGGAA
			
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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