DNA Binding Motif

Accessions: HOXB13_ETV1 (HumanTF2 1.0)
Names: HOXB13_ETV1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: rCCGGAAgTawwaAAa
Weblogo:
PSSM: P0 A C G T
01 95 9 85 23 r
02 9 133 47 4 C
03 43 180 8 2 C
04 3 0 180 0 G
05 0 0 180 14 G
06 180 0 0 7 A
07 180 23 0 35 A
08 39 39 141 0 g
09 0 42 0 138 T
10 105 17 42 14 a
11 85 4 27 64 w
12 109 12 7 180 w
13 180 10 20 57 a
14 180 3 0 5 A
15 180 11 2 57 A
16 88 21 33 37 a
Type: Heterodimer
Binding TFs: ETV1_TF2 (Ets-domain)
HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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