DNA Binding Motif

						

			
Accessions: MGA_DLX2_2 (HumanTF2 1.0)

			
Names: MGA_DLX2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: syAATTAwaGGTGyGA
Weblogo: 
PSSM: P0      A      C      G      T
01    247    523    840     44      s
02    145    781     76    549      y
03   1169      0    238    301      A
04   1363     69    145     29      A
05      0      3      0   1418      T
06      6     40      0   1419      T
07   1185     16     62    394      A
08    554     85    337    442      w
09   1085     51    161    303      a
10    144    193   1206     77      G
11     23     47   1411      0      G
12     27    164     19   1354      T
13     18      8   1395     21      G
14     82    404     81   1006      y
15     83     12   1282    307      G
16   1383      6     84     15      A
Type: Heterodimer
Binding TFs: DLX2_TF2 (Homeobox domain, Homeobox protein distal-less-like N terminal )
MGA_TF1 (T-box)
DLX2_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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