DNA Binding Motif

						

			
Accessions: HOXB2_PITX1_2_3 (HumanTF2 1.0)

			
Names: HOXB2_PITX1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: taAtkrssrmGGATTA
Weblogo: 
PSSM: P0      A      C      G      T
01     36     49     51    269      t
02    269     64    104     17      a
03    269      0     13     28      A
04     48     63     37    269      t
05     19     53    154    114      k
06    144     55    124     47      r
07     55     89     90     35      s
08     55     76     78     60      s
09     89     58     86     36      r
10     95     89     41     44      m
11     47      7    269     27      G
12      0      6    269     35      G
13    269     48     15      0      A
14     18      4      0    269      T
15     15      0     17    269      T
16    269      7      2     36      A
Type: Heterodimer
Binding TFs: HOXB2_TF1 (Homeobox domain)
PITX1_TF1 / PITX1_TF2 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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