DNA Binding Motif

Accessions: 2hap_D (3D-footprint 20231221)
Names: PROTEIN (HEME ACTIVATOR PROTEIN)
Organisms: Saccharomyces cerevisiae
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: STRUCTURE OF A HAP1-18/DNA COMPLEX REVEALS THAT PROTEIN/DNA INTERACTIONS CAN HAVE DIRECT ALLOSTERIC EFFECTS ON TRANSCRIPTIONAL ACTIVATION
Length: 9
Consensus: ATAAnaGCG
Weblogo:
PSSM: P0 A C G T
01 82 7 0 7 A
02 0 0 0 96 T
03 96 0 0 0 A
04 66 7 14 9 A
05 24 24 24 24 n
06 59 14 9 14 a
07 0 0 96 0 G
08 1 88 7 0 C
09 1 7 88 0 G
Binding TFs: 2hap_D (Fungal Zn(2)-Cys(6) binuclear cluster domain)
Binding Sites: 2hap_A
2hap_B
Publications: King D.A, Zhang L, Guarente L, Marmorstein R. Structure of HAP1-18-DNA implicates direct allosteric effect of protein-DNA interactions on transcriptional activation. Nature structural biology 6:22-7 (1999). [Pubmed]

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