DNA Binding Motif

Accessions: GCM1_MAX_2_3 (HumanTF2 1.0)
Names: GCM1_MAX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: aTGCGGGyrgsgmgCACGTGg
Weblogo:
PSSM: P0 A C G T
01 4499 886 1721 235 a
02 356 177 257 6219 T
03 1798 221 6219 5 G
04 977 6219 709 461 C
05 468 138 6219 975 G
06 2 15 6219 43 G
07 0 11 6219 15 G
08 217 1805 324 3873 y
09 1661 917 2729 912 r
10 1012 1181 3055 972 g
11 1288 1574 2223 1134 s
12 1507 863 2579 1271 g
13 2070 1708 1530 911 m
14 859 1419 2968 974 g
15 49 6219 12 0 C
16 6219 0 115 48 A
17 10 6219 62 362 C
18 347 0 6219 3 G
19 64 32 14 6219 T
20 4 5 6219 23 G
21 941 1474 2585 1220 g
Type: Heterodimer
Binding TFs: GCM1_TF1 (GCM motif protein)
MAX_TF2 (Helix-loop-helix DNA-binding domain)
MAX_Full (Helix-loop-helix DNA-binding domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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