DNA Binding Motif

Accessions: POU2F1_SOX15_2 (HumanTF2 1.0)
Names: POU2F1_SOX15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 13
Consensus: wtGmATrACAAwr
Weblogo:
PSSM: P0 A C G T
01 223 73 63 271 w
02 128 124 134 494 t
03 67 10 494 21 G
04 250 244 14 43 m
05 494 28 13 49 A
06 5 6 16 494 T
07 494 54 228 61 r
08 494 14 12 107 A
09 34 494 73 111 C
10 494 23 3 9 A
11 494 13 4 12 A
12 344 64 41 494 w
13 298 80 196 52 r
Type: Heterodimer
Binding TFs: POU2F1_TF1 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
SOX15_TF2 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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