DNA Binding Motif

						

			
Accessions: ELK1_PAX1 (HumanTF2 1.0), UN0500.1 (JASPAR 2024)

			
Names: ELK1_PAX1, ELK1::PAX1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 20
Consensus: aCCGGAACyACGCwTsRsYg
Weblogo: 
PSSM: P0      A      C      G      T
01   1132    225    329    176      a
02     28   1306    199     20      C
03     42   1463      0      0      C
04      0      1   1506      1      G
05      0      0   1506      0      G
06   1506      0      0      0      A
07   1505      0      3      1      A
08      0   1449    254     98      C
09      0    492      0   1014      y
10   1505     11     45      0      A
11      0   1396     22    304      C
12      2      0   1504      5      G
13      5   1364    358      3      C
14    709     67    105    737      w
15     45    288      0   1201      T
16      2    760    740      6      s
17   1420     31    513      8      R
18    145    547    478    336      s
19     30    468      8   1344      Y
20    200      0   1189    385      g
Type: Heterodimer
Binding TFs: P19419 (Ets-domain)
ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
PAX1_TF2 ('Paired box' domain, Homeodomain-like domain)
ELK1_TF1 (Ets-domain)
P19419
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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