DNA Binding Motif

						

			
Accessions: 2pe5_AB (3D-footprint 20231221)

			
Names: Lactose operon repressor
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of the Lac Repressor bound to ONPG in repressed state
Length: 13
Consensus: GTGAGCGctCACA
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0     96      0      G
02      0      0      0     96      T
03      0      0     96      0      G
04     72      8      8      8      A
05      0      0     96      0      G
06      0     96      0      0      C
07      8      0     88      0      G
08      8     64      8     16      c
09     16      8      8     64      t
10      0     96      0      0      C
11     96      0      0      0      A
12      0     96      0      0      C
13     96      0      0      0      A
Type: Heterodimer
Binding TFs: 2pe5_A (Bacterial regulatory proteins, lacI family, Periplasmic binding proteins and sugar binding domain of LacI family, Periplasmic binding protein-like domain, Periplasmic binding protein domain)
2pe5_B (Bacterial regulatory proteins, lacI family, Periplasmic binding proteins and sugar binding domain of LacI family, Periplasmic binding protein-like domain, Periplasmic binding protein domain)
Binding Sites: 2pe5_D
2pe5_E
			
Publications: Daber R, Stayrook S, Rosenberg A, Lewis M. Structural analysis of lac repressor bound to allosteric effectors. Journal of molecular biology 370:609-19 (2007). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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