DNA Binding Motif

Accessions: 4wls_AB (3D-footprint 20231221)
Names: HTH-type transcriptional regulator CueR
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the metal-free (repressor) form of E. Coli CUER, a copper efflux regulator, bound to COPA promoter DNA
Length: 19
Consensus: GnnnCCnCnnTTTGGnnnG
Weblogo:
PSSM: P0 A C G T
01 3 3 87 3 G
02 24 24 24 24 n
03 24 24 24 24 n
04 24 24 24 24 n
05 0 92 1 3 C
06 0 96 0 0 C
07 24 24 24 24 n
08 4 86 3 3 C
09 24 24 24 24 n
10 24 24 24 24 n
11 3 4 3 86 T
12 4 16 3 73 T
13 12 14 3 67 T
14 3 4 86 3 G
15 0 0 96 0 G
16 24 24 24 24 n
17 24 24 24 24 n
18 24 24 24 24 n
19 4 16 73 3 G
Binding TFs: 4wls_A / 4wls_B (MerR family regulatory protein, MerR, DNA binding, MerR HTH family regulatory protein)
Binding Sites: 4wls_X
4wls_Y
Publications: Philips SJ, Canalizo-Hernandez M, Yildirim I, Schatz GC, Mondragón A, O'Halloran TV. TRANSCRIPTION. Allosteric transcriptional regulation via changes in the overall topology of the core promoter 349:877-81 (Science.). [Pubmed]

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