DNA Binding Motif

						

			
Accessions: 4wls_AB (3D-footprint 20231221)

			
Names: HTH-type transcriptional regulator CueR
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the metal-free (repressor) form of E. Coli CUER, a copper efflux regulator, bound to COPA promoter DNA
Length: 19
Consensus: GnnnCCnCnnTTTGGnnnG
Weblogo: 
PSSM: P0      A      C      G      T
01      3      3     87      3      G
02     24     24     24     24      n
03     24     24     24     24      n
04     24     24     24     24      n
05      0     92      1      3      C
06      0     96      0      0      C
07     24     24     24     24      n
08      4     86      3      3      C
09     24     24     24     24      n
10     24     24     24     24      n
11      3      4      3     86      T
12      4     16      3     73      T
13     12     14      3     67      T
14      3      4     86      3      G
15      0      0     96      0      G
16     24     24     24     24      n
17     24     24     24     24      n
18     24     24     24     24      n
19      4     16     73      3      G
Binding TFs: 4wls_A / 4wls_B (MerR family regulatory protein, MerR, DNA binding, MerR HTH family regulatory protein)
Binding Sites: 4wls_X
4wls_Y
			
Publications: Philips SJ, Canalizo-Hernandez M, Yildirim I, Schatz GC, Mondragón A, O'Halloran TV. TRANSCRIPTION. Allosteric transcriptional regulation via changes in the overall topology of the core promoter 349:877-81 (Science.). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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