DNA Binding Motif

						

			
Accessions: POU2F1_DBD_1 (HumanTF 1.0), MA0785.1 (JASPAR 2024)

			
Names: POU2F1
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 2, HT-SELEX
Length: 12
Consensus: awTATGcwAATt
Weblogo: 
PSSM: P0      A      C      G      T
01   5076   1938   1494   2075      a
02   5351   1046   2142   5231      w
03    756   1347    474  10582      T
04  10582     12     29     43      A
05    153    501    213  10582      T
06    186     82  10582   1326      G
07    300  10582   1351   3375      c
08   6932     33     46   3651      w
09  10582    108    879    787      A
10  10582     37     51    158      A
11   1422    457    755  10582      T
12   1976   1840   2504   4262      t
Type: Heterodimer
Binding TFs: POU2F1_DBD (Homeobox domain, Pou domain - N-terminal to homeobox domain)
P14859 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
P14859
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Verrijzer C. P., Alkema M. J., van Weperen W. W., van Leeuwen H. C., Strating M. J. J., van der Vliet P. C. The DNA binding specificity of the bipartite POU domain and its subdomains. EMBO J. 11:4993-5003 (1992). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.