DNA Binding Motif

						

			
Accessions: KLF13_full (HumanTF 1.0), MA0657.1 (JASPAR 2024)

			
Names: KLF13
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 4, HT-SELEX
Length: 18
Consensus: rtRmCACGCCCCYTTttg
Weblogo: 
PSSM: P0      A      C      G      T
01   1508    248    915    590      r
02    733     46    796   1766      t
03   1891      0   4630     59      R
04    496    923     58    102      m
05     75    924      2     61      C
06   2384      0     11      0      A
07      0   1353      7      3      C
08     24      2   3028      9      G
09      0   1596      0      7      C
10      4   1469      0      0      C
11      1   1760      0     16      C
12    509   1766      0     10      C
13      3    638      3   1403      Y
14    156    350     54   2040      T
15    247    235    270   2968      T
16    735    554    841   2247      t
17    404    176    483   1672      t
18    285    221   1226    560      g
Type: Heterodimer
Binding TFs: Q9Y2Y9 (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
KLF13_full (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Q9Y2Y9
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Lomberk G, Urrutia R. The family feud: turning off Sp1 by Sp1-like KLF proteins. Biochem J : (2005). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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