DNA Binding Motif

						

			
Accessions: E2F1_EOMES_1 (HumanTF2 1.0)

			
Names: E2F1_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: vrGTGtGaAwgGCGCsywkCac
Weblogo: 
PSSM: P0      A      C      G      T
01    273    186    190     52      v
02    419    222    701    106      r
03     47     50    701     24      G
04     28    124    108    701      T
05      3      0    701      4      G
06    153    194     62    701      t
07     39     71    701    130      G
08    455     51     68    127      a
09    510     27     34    130      A
10    250      0    176    282      w
11     61    284    701    102      g
12      0     30    701      0      G
13      5    701      9      0      C
14      7      0    701      0      G
15      0    701    133      4      C
16      0    265    436     73      s
17     60    179    100    363      y
18    279    128     93    202      w
19    145     80    237    240      k
20      0    701      3     86      C
21    525     33    176     80      a
22     35    701    193    268      c
Type: Heterodimer
Binding TFs: E2F1_TF1 (E2F/DP family winged-helix DNA-binding domain)
EOMES_TF2 (T-box)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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