DNA Binding Motif

						

			
Accessions: TEAD4_DLX2_2_3 (HumanTF2 1.0)

			
Names: TEAD4_DLX2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: rmATwcywyssTAATtr
Weblogo: 
PSSM: P0      A      C      G      T
01    544    110    437    173      r
02    439    981    215     25      m
03    981      0    196      1      A
04     60     10     20    981      T
05    771     29    367    981      w
06    170    981    369    306      c
07    142    585     95    396      y
08    249    230    227    275      w
09    226    263    229    263      y
10    235    256    250    239      s
11    237    250    260    234      s
12    103    248     17    981      T
13    981     36    215     38      A
14    981     19     15      0      A
15     69     35    147    981      T
16    218    267    400    981      t
17    482     56    499    129      r
Type: Heterodimer
Binding TFs: DLX2_TF2 (Homeobox domain, Homeobox protein distal-less-like N terminal )
TEAD4_TF1 (TEA/ATTS domain family)
DLX2_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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