DNA Binding Motif

						

			
Accessions: GCM2_FIGLA_1 (HumanTF2 1.0)

			
Names: GCM2_FIGLA
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 15
Consensus: aTrCGGGtmCAssTG
Weblogo: 
PSSM: P0      A      C      G      T
01   2046    572    707    142      a
02    198    224    168   2753      T
03    832    121   1921     11      r
04    421   2753    491    347      C
05    289     86   2753    224      G
06     11     12   2753     47      G
07      0     26   2753      0      G
08    479    618    176   1480      t
09    935   1050    429    340      m
10    144   2753     39    131      C
11   2753    187    126     93      A
12      5   1287   1466     63      s
13    108   1238   1515     47      s
14    134    197    214   2753      T
15    185     95   2753    139      G
Type: Heterodimer
Binding TFs: FIGLA_TF2 (Helix-loop-helix DNA-binding domain)
GCM2_TF1 (GCM motif protein)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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