DNA Binding Motif

						

			
Accessions: POU2F1_DLX2_2 (HumanTF2 1.0)

			
Names: POU2F1_DLX2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: tGmATATkCahwmkTAATTr
Weblogo: 
PSSM: P0      A      C      G      T
01     76    653    770   1774      t
02    226      7   1774     95      G
03   1172    602     48     20      m
04   1774    135     70    181      A
05     15      3      0   1774      T
06   1774      7      0      8      A
07      3      0     39   1774      T
08     10      8   1084    690      k
09      0   1774     59     39      C
10   1774    740    373    143      a
11    511    618    196    450      h
12    854    125    136    659      w
13    568    593    239    374      m
14    344    263    455    712      k
15     45    352     51   1774      T
16   1774      3     28     37      A
17   1774      0     95     65      A
18     16     58    135   1774      T
19     15    247    271   1504      T
20    590     33   1185     27      r
Type: Heterodimer
Binding TFs: DLX2_TF2 (Homeobox domain, Homeobox protein distal-less-like N terminal )
POU2F1_TF1 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
DLX2_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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