DNA Binding Motif

						

			
Accessions: ETV2_TBX21_2_3 (HumanTF2 1.0)

			
Names: ETV2_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 24
Consensus: aCCGGAwryrmvmhyYmACACCTy
Weblogo: 
PSSM: P0      A      C      G      T
01   4626    959   1249    551      a
02    940   5874    626    175      C
03    792   5874     35      0      C
04      1      0   5874      5      G
05      6     64   5874     29      G
06   5874      0      0      8      A
07   3977    342      0   1559      w
08   2081    640   3079     74      r
09    417   2622    548   2287      y
10   2072   1326   1579    897      r
11   1638   2234   1087    915      m
12   1525   1713   1838    798      v
13   1892   1761    940   1282      m
14   1581   1587   1077   1629      h
15   1031   1654   1465   1725      y
16    100   1646     80   4048      Y
17   1628   3297    737    211      m
18   5874    268    958    281      A
19      0   5874      5     12      C
20   5874     19    602      0      A
21    101   5874     64     10      C
22    686   5874    879    505      C
23    744   1322    353   5874      T
24   1161   1992    547   2175      y
Type: Heterodimer
Binding TFs: TBX21_TF2 (T-box)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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