DNA Binding Motif

Accessions: GCM1_MAX_2_3_4 (HumanTF2 1.0)
Names: GCM1_MAX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 15
Consensus: CACGTGgwTgcgGGy
Weblogo:
PSSM: P0 A C G T
01 20 3121 31 0 C
02 3121 45 41 23 A
03 12 3121 0 91 C
04 108 19 3121 12 G
05 31 38 42 3121 T
06 0 16 3121 5 G
07 119 763 1802 437 g
08 979 577 657 908 w
09 219 481 123 2297 T
10 1036 285 3121 156 g
11 672 3121 548 664 c
12 525 86 3121 1222 g
13 48 240 3121 186 G
14 105 144 3121 42 G
15 431 1157 326 1963 y
Type: Heterodimer
Binding TFs: GCM1_TF1 (GCM motif protein)
MAX_TF2 (Helix-loop-helix DNA-binding domain)
MAX_Full (Helix-loop-helix DNA-binding domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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