DNA Binding Motif

						

			
Accessions: GCM1_FOXO1_2 (HumanTF2 1.0)

			
Names: GCM1_FOXO1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: gTmAATAmGGGyas
Weblogo: 
PSSM: P0      A      C      G      T
01    444    150   1184     66      g
02    538    206     71   2313      T
03   1043   1856     81    103      m
04   2744    297     76    112      A
05   2762     95     64     14      A
06     29     75      0   2297      T
07   2694    104     27      0      A
08   1935   1631     79    159      m
09     28    102   1221    229      G
10     19     17   1257     44      G
11     48      0   1282     27      G
12     63    960     12   1457      y
13   1709    283    332    236      a
14    292    681    548    429      s
Type: Heterodimer
Binding TFs: FOXO1_TF1 / FOXO1_TF2 (Fork head domain)
GCM1_TF1 (GCM motif protein)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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