DNA Binding Motif

						

			
Accessions: GCM1_HOXB13_1 (HumanTF2 1.0)

			
Names: GCM1_HOXB13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 15
Consensus: rTGcGGGTmATaAaw
Weblogo: 
PSSM: P0      A      C      G      T
01    358     70    274     19      r
02     86     53     83    632      T
03    163     44    469      3      G
04     91    328    105    108      c
05     58     64    632     84      G
06      0      5    632      0      G
07     23      2    632      1      G
08     25    122     43    632      T
09    318    230     32     53      m
10    557      2     50     23      A
11     37     96     81    632      T
12    632     83    176    251      a
13    632     80     96     92      A
14    632    131    220    126      a
15    200    146    128    158      w
Type: Heterodimer
Binding TFs: GCM1_TF1 (GCM motif protein)
HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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