DNA Binding Motif

						

			
Accessions: E2F1_EOMES_2 (HumanTF2 1.0)

			
Names: E2F1_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 24
Consensus: rsGYGtsrwGGCGsywTgdCrbgg
Weblogo: 
PSSM: P0      A      C      G      T
01   1742    420   1131    769      r
02    601   1340   2873    426      s
03    175    288   2873    139      G
04    125   1171     55   2873      Y
05      3      8   2873     45      G
06   1099    728   1301   2873      t
07    372    720   1163    618      s
08   1913     32    743    185      r
09    744    232    609   1288      w
10    253    585   2873     71      G
11      0     85   2873      0      G
12      2   2873      0      0      C
13      0     11   2873      7      G
14      4   1934    940      9      s
15    122   1282    692    777      y
16   1093    420    457    902      w
17    529    217     74   2873      T
18    690    537    936    710      g
19   1054     28    998    793      d
20     25   2873     24    231      C
21   1504     74   1369    107      r
22    506   1493   1381   1148      b
23    402    659   1106    706      g
24    683    566    912    712      g
Type: Heterodimer
Binding TFs: E2F1_TF1 (E2F/DP family winged-helix DNA-binding domain)
EOMES_TF2 (T-box)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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