DNA Binding Motif

Accessions: 1ea4_DEFG (3D-footprint 20231221)
Names: TRANSCRIPTIONAL REPRESSOR COPG
Organisms: Streptococcus agalactiae
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: TRANSCRIPTIONAL REPRESSOR COPG/22bp dsDNA COMPLEX
Length: 17
Consensus: GtTGCAnnnnGTGCAAG
Weblogo:
PSSM: P0 A C G T
01 8 4 80 4 G
02 12 12 8 64 t
03 0 0 0 96 T
04 0 0 84 12 G
05 0 96 0 0 C
06 96 0 0 0 A
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 24 24 24 24 n
11 12 8 68 8 G
12 0 0 0 96 T
13 0 0 96 0 G
14 0 96 0 0 C
15 76 4 12 4 A
16 76 12 4 4 A
17 0 0 96 0 G
Type: Heterodimer
Binding TFs: 1ea4_D (Ribbon-helix-helix protein, copG family)
1ea4_E (Ribbon-helix-helix protein, copG family)
1ea4_F (Ribbon-helix-helix protein, copG family)
1ea4_G (Ribbon-helix-helix protein, copG family)
Binding Sites: 1ea4_W
1ea4_X
Publications: Costa M, Solà M, del Solar G, Eritja R, Hernández-Arriaga A.M, Espinosa M, Gomis-Rüth F.X, Coll M. Plasmid transcriptional repressor CopG oligomerises to render helical superstructures unbound and in complexes with oligonucleotides. Journal of molecular biology 310:403-17 (2001). [Pubmed]

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