DNA Binding Motif

Accessions: 5kkq_D (3D-footprint 20231221)
Names: Transcriptional repressor CTCF
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Homo sapiens CCCTC-binding factor (CTCF) ZnF3-7 and DNA complex structure
Length: 14
Consensus: CCAGCAGGGGGCGC
Weblogo:
PSSM: P0 A C G T
01 11 67 9 9 C
02 0 96 0 0 C
03 87 0 9 0 A
04 0 0 96 0 G
05 0 96 0 0 C
06 96 0 0 0 A
07 0 0 96 0 G
08 0 0 96 0 G
09 9 9 67 11 G
10 0 0 96 0 G
11 0 0 96 0 G
12 0 86 1 9 C
13 0 0 96 0 G
14 1 86 0 9 C
Binding TFs: 5kkq_D (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc-finger domain)
Binding Sites: 5kkq_E
5kkq_F
Publications: Hashimoto H, Wang D, Horton JR, Zhang X, Corces VG, Cheng X. Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. Mol Cell 66:711-720 (2017). [Pubmed]

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