DNA Binding Motif

						

			
Accessions: 1u8r_GHIJ (3D-footprint 20231221)

			
Names: Iron-dependent repressor ideR
Organisms: Mycobacterium tuberculosis, strain ATCC 25618 / H37Rv
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of an IdeR-DNA Complex Reveals a Conformational Change in Activated IdeR for Base-specific Interactions
Length: 17
Consensus: TTAGCACAGGCTGCCCT
Weblogo: 
PSSM: P0      A      C      G      T
01      2      2      4     88      T
02      9      9     11     67      T
03     96      0      0      0      A
04      9      7     69     11      G
05      2     88      4      2      C
06     96      0      0      0      A
07      7     67      9     13      C
08     96      0      0      0      A
09      0      0     96      0      G
10      0      0     96      0      G
11      0     96      0      0      C
12      0      0      0     96      T
13      9      9     69      9      G
14      0     96      0      0      C
15      0     96      0      0      C
16      7     69     11      9      C
17      0      0      0     96      T
Type: Heterodimer
Binding TFs: 1u8r_G / 1u8r_I (Iron dependent repressor, N-terminal DNA binding domain, Iron dependent repressor, metal binding and dimerisation domain, FeoA domain, Winged helix DNA-binding domain)
1u8r_H / 1u8r_J (Iron dependent repressor, N-terminal DNA binding domain, Iron dependent repressor, metal binding and dimerisation domain, FeoA domain, Winged helix DNA-binding domain)
Binding Sites: 1u8r_K
1u8r_L
			
Publications: Wisedchaisri G, Holmes R.K, Hol W.G. Crystal structure of an IdeR-DNA complex reveals a conformational change in activated IdeR for base-specific interactions. Journal of molecular biology 342:1155-69 (2004). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.