DNA Binding Motif

Accessions: MA0620.1 (JASPAR 2024)
Names: Mitf
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: PBM
Length: 10
Consensus: rrTCACGtGg
Weblogo:
PSSM: P0 A C G T
01 274 193 312 220 r
02 398 81 462 59 r
03 77 95 100 728 T
04 7 989 3 2 C
05 882 52 16 50 A
06 8 725 73 194 C
07 156 33 798 13 G
08 238 191 109 461 t
09 28 28 884 60 G
10 245 215 341 199 g
Type: Heterodimer
Binding TFs: Q08874 (Helix-loop-helix DNA-binding domain, Domain of unknown function (DUF3371))
Q08874
Publications: McGill G. G., Horstmann M., Widlund H. R., Du J., Motyckova G., Nishimura E. K., Lin Y. L., Ramaswamy S., Avery W., Ding H. F., Jordan S. A., Jackson I. J., Korsmeyer S. J., Golub T. R., Fisher D. E. Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability.. Cell 109:707-718 (2002). [Pubmed]

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