DNA Binding Motif

						

			
Accessions: 5edn_AJ (3D-footprint 20231221)

			
Names: Homeobox protein Hox-B13
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of HOXB13-DNA(TCG) complex
Length: 22
Consensus: ATAAAnnnCnnTTnnnnTTTAT
Weblogo: 
PSSM: P0      A      C      G      T
01     75      4     13      4      A
02      0      0      0     96      T
03     96      0      0      0      A
04     96      0      0      0      A
05     70      4      8     14      A
06     24     24     24     24      n
07     24     24     24     24      n
08     24     24     24     24      n
09      0     96      0      0      C
10     24     24     24     24      n
11     24     24     24     24      n
12      0      0      0     96      T
13      8      8      5     75      T
14     24     24     24     24      n
15     24     24     24     24      n
16     24     24     24     24      n
17     24     24     24     24      n
18      8      8     12     68      T
19      0      0      0     96      T
20      4      4      5     83      T
21     96      0      0      0      A
22      4      5      4     83      T
Type: Heterodimer
Binding TFs: 5edn_A (Homeobox domain)
5edn_J (Homeobox domain)
Binding Sites: 5edn_K
5edn_L
			
Publications: Morgunova E, Yin Y, Das PK, Jolma A, Zhu F, Popov A, Xu Y, Nilsson L, Taipale J. Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima. Elife : (2018). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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