DNA Binding Motif

						

			
Accessions: NR6A1_2 (HT-SELEX2 May2017), MA1541.1 (JASPAR 2024)

			
Names: NR6A1
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1, JASPAR 2024 2
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HT-SELEX
Length: 17
Consensus: gtcAAGkTCAAGktCRw
Weblogo: 
PSSM: P0      A      C      G      T
01    171    197    313    216      g
02    255    473    348    896      t
03    124    896    342    132      c
04    896      4     44     11      A
05    896     91     72     51      A
06     13      9    896     62      G
07     19     12    443    453      k
08      1     74     26    896      T
09      7    896     29     40      C
10    896      0      2     14      A
11    896     96     35     65      A
12     21     15    896     62      G
13     29     11    524    373      k
14     91    185    355    896      t
15     39    896    109    254      C
16    896     20    359     41      R
17    282    177    207    230      w
Type: Heterodimer
Binding TFs: Q15406 (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
NR6A1 (Zinc finger, C4 type (two domains))
Q15406
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]


Hummelke GC, Cooney AJ. Germ cell nuclear factor is a transcriptional repressor essential for embryonic development. Front Biosci : (2001). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.