DNA Binding Motif

						

			
Accessions: 3g6t_AB (3D-footprint 20231221)

			
Names: Glucocorticoid receptor
Organisms: Rattus norvegicus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: GR gamma DNA-binding domain:FKBP5 16bp complex-34
Length: 11
Consensus: GnACAnnnTGT
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0     96      0      G
02     24     24     24     24      n
03     75      7      7      7      A
04      0     96      0      0      C
05     73      9      7      7      A
06     24     24     24     24      n
07     24     24     24     24      n
08     24     24     24     24      n
09      9      7      7     73      T
10      0      0     96      0      G
11      7      7      7     75      T
Type: Heterodimer
Binding TFs: 3g6t_A (Zinc finger, C4 type (two domains))
3g6t_B (Zinc finger, C4 type (two domains))
Binding Sites: 3g6t_C
3g6t_D
			
Publications: Meijsing S.H, Pufall M.A, So A.Y, Bates D.L, Chen L, Yamamoto K.R. DNA binding site sequence directs glucocorticoid receptor structure and activity. Science (New York, N.Y.) 324:407-10 (2009). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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