DNA Binding Motif

						

			
Accessions: GCM2_ELK1 (HumanTF2 1.0), UN0552.1 (JASPAR 2024)

			
Names: GCM2_ELK1, GCM2::ELK1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 15
Consensus: rTryGGGCGGAAGTr
Weblogo: 
PSSM: P0      A      C      G      T
01    578    142    328    220      r
02    115    105     66    983      T
03    413    164    856      0      r
04    241    458    229    341      y
05    214     32   1269     61      G
06     27      0   1269     35      G
07     71      6   1269      4      G
08    191   1269    154     64      C
09     25     37   1269     56      G
10     71      0   1269     86      G
11   1269     47     44     32      A
12   1269     48     51    297      A
13    323     53    946     20      G
14    196    203    109   1269      T
15    476    110    484    199      r
Type: Heterodimer
Binding TFs: P19419 (Ets-domain)
ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
GCM2_TF1 (GCM motif protein)
ELK1_TF1 (Ets-domain)
P19419
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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