DNA Binding Motif

Accessions: GCM2_ELK1 (HumanTF2 1.0), UN0552.1 (JASPAR 2024)
Names: GCM2_ELK1, GCM2::ELK1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 15
Consensus: rTryGGGCGGAAGTr
Weblogo:
PSSM: P0 A C G T
01 578 142 328 220 r
02 115 105 66 983 T
03 413 164 856 0 r
04 241 458 229 341 y
05 214 32 1269 61 G
06 27 0 1269 35 G
07 71 6 1269 4 G
08 191 1269 154 64 C
09 25 37 1269 56 G
10 71 0 1269 86 G
11 1269 47 44 32 A
12 1269 48 51 297 A
13 323 53 946 20 G
14 196 203 109 1269 T
15 476 110 484 199 r
Type: Heterodimer
Binding TFs: P19419 (Ets-domain)
ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
GCM2_TF1 (GCM motif protein)
ELK1_TF1 (Ets-domain)
P19419
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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