DNA Binding Motif

Accessions: ETV5_FOXI1_2_3 (HumanTF2 1.0)
Names: ETV5_FOXI1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 13
Consensus: tGtkkmCGGAwGt
Weblogo:
PSSM: P0 A C G T
01 55 68 127 510 t
02 95 2 510 102 G
03 105 38 126 510 t
04 65 71 268 510 k
05 94 0 510 312 k
06 178 167 92 73 m
07 0 510 40 12 C
08 0 0 510 19 G
09 4 3 510 39 G
10 510 0 30 0 A
11 339 15 21 171 w
12 49 33 461 0 G
13 92 60 64 295 t
Type: Heterodimer
Binding TFs: ETV5_TF1 (Ets-domain)
FOXI1_TF2 (Fork head domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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