DNA Binding Motif

						

			
Accessions: HOXA13_full_1 (HumanTF 1.0), MA0650.1 (JASPAR 2024)

			
Names: HOXA13
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 4, HT-SELEX
Length: 10
Consensus: cyaATAAAam
Weblogo: 
PSSM: P0      A      C      G      T
01     62    247     71      4      c
02      1    247      8    125      y
03    247     70      9     43      a
04    247      0      0     31      A
05      0      0      0    247      T
06    247      9      5     15      A
07    247      0      0     16      A
08    247      3      0      0      A
09    247     60     44     34      a
10    104     72     23     48      m
Type: Heterodimer
Binding TFs: P31271 (Homeobox domain, Hox protein A13 N terminal)
HOXA13_full (Homeobox domain, Hox protein A13 N terminal)
P31271
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Knosp W. M., Saneyoshi C., Shou S., Bachinger H. P., Stadler H. S. Elucidation, quantitative refinement, and in vivo utilization of the HOXA13 DNA binding site.. J. Biol. Chem. 282:6843-6853 (2007). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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