DNA Binding Motif

						

			
Accessions: MEIS1_MAX (HumanTF2 1.0)

			
Names: MEIS1_MAX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: wTGACrbgtsrvCACGTGc
Weblogo: 
PSSM: P0      A      C      G      T
01  17030  11459  14581  17435      w
02   5681   6231   2845  60505      T
03    698   1130  60505   1030      G
04  60505   1012   2768  12572      A
05    766  60505    196   2868      C
06  38782    315  21723    925      r
07   2409  19969  16553  21573      b
08  11717  12358  28182   8248      g
09  12768   9312  11581  26844      t
10  10320  21224  16881  12080      s
11  17216  11765  21226  10298      r
12  16579  17050  22866   4008      v
13    329  60505    183     89      C
14  60505    220   1100    153      A
15      0  60505    264   4318      C
16   3839     95  60505     68      G
17   1924   2155    152  60505      T
18      0    405  60505    393      G
19  10604  30753  11387   7760      c
Type: Heterodimer
Binding TFs: MAX_TF2 (Helix-loop-helix DNA-binding domain)
MEIS1_TF1 (Homeobox domain, Homeobox KN domain)
MAX_Full (Helix-loop-helix DNA-binding domain)
MEIS1_Crystal (Homeobox domain, Homeobox KN domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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