DNA Binding Motif

						

			
Accessions: ETV2_GSC2_2_3_4 (HumanTF2 1.0)

			
Names: ETV2_GSC2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: rsCGGAwrtrsgGATTA
Weblogo: 
PSSM: P0      A      C      G      T
01    555     90    489    151      r
02    209    678    366     45      s
03    159   1045     28      0      C
04      0      0   1045      0      G
05      0      0   1045     27      G
06   1045      0      5     44      A
07   1045    141      2    436      w
08    576     10    458      0      r
09     82    148    140    674      t
10    405    173    375     92      r
11    183    426    269    167      s
12    386    175   1045    102      g
13    102    240   1045    105      G
14   1045    311     23     91      A
15     18     27     34   1045      T
16     59     48     19   1045      T
17   1045     15     28    198      A
Type: Heterodimer
Binding TFs: GSC2_TF2 (Homeobox domain)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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