DNA Binding Motif

						

			
Accessions: TFAP4_FLI1_1 (HumanTF2 1.0)

			
Names: TFAP4_FLI1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 15
Consensus: rscGGAwrCAgsTGg
Weblogo: 
PSSM: P0      A      C      G      T
01    399     63    372    102      r
02     99    489    282     60      s
03    287    771    152     80      c
04     27     34    771     32      G
05     30     38    771     90      G
06    771     41     58     33      A
07    419     45     38    352      w
08    369     63    402     40      r
09      0    771     20      0      C
10    771     17     48      9      A
11     17    197    574     81      g
12    118    476    295      2      s
13     26     51     18    771      T
14      0      3    771     10      G
15    165    115    317    174      g
Type: Heterodimer
Binding TFs: FLI1_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
FLI1_Full (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
TFAP4_TF1 (Helix-loop-helix DNA-binding domain)
TFAP4_Full (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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