DNA Binding Motif
| Accessions: | UP00089A_2 (UniPROBE 20160601) |
| Names: | AI323641, hepatocyte nuclear factor 1, Hepatocyte nuclear factor 1-alpha, Hnf-1, Hnf-1a, HNF1, HNF1-alpha, HNF1[a], Hnf1a, Hnf1alpha, LFB1, Liver-specific transcription factor LF-B1, Tcf-1, Tcf1, transcription factor 1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Length: | 14 |
| Consensus: | tkrycygGATTAdr |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 0.24 0.20 0.20 0.36 t 02 0.15 0.22 0.28 0.36 k 03 0.40 0.12 0.42 0.06 r 04 0.18 0.37 0.17 0.28 y 05 0.19 0.51 0.21 0.09 c 06 0.09 0.36 0.25 0.31 y 07 0.18 0.18 0.62 0.02 g 08 0.02 0.02 0.93 0.03 G 09 0.87 0.01 0.08 0.04 A 10 0.03 0.02 0.04 0.90 T 11 0.01 0.03 0.05 0.91 T 12 0.90 0.02 0.04 0.05 A 13 0.25 0.10 0.37 0.28 d 14 0.28 0.17 0.34 0.21 r |
| Binding TFs: | UP00089A (Homeobox domain) |
| Binding Sites: | AAGTTAAC ACTAACTA ACTAGTTA AGTTAACC AGTTAACG CCGGTTAA CGGTTAAC CTAACTAA CTAACTAG CTAGTTAA CTGGTTAA CTTAACTA GGTTAACA GTAGTTAA GTTAACCA GTTAACTA TAACTAGA TAAGTTAA TCGGTTAA TTAACTAA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
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