DNA Binding Motif

						

			
Accessions: TEAD4_HOXB13_2_3 (HumanTF2 1.0)

			
Names: TEAD4_HOXB13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: rGwATGCymrTaAa
Weblogo: 
PSSM: P0      A      C      G      T
01    167      8    189     16      r
02     65     19    356     61      G
03    356      0      0    186      w
04    356      0     17      0      A
05      3     23      3    356      T
06      0      6    356    109      G
07     10    356     41     79      C
08     78    101     32    145      y
09    144    157     19     37      m
10    173      0    183     46      r
11      9     58     13    356      T
12    356     38     34    135      a
13    356     36     21     42      A
14    356     67     36     80      a
Type: Heterodimer
Binding TFs: HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
TEAD4_TF1 (TEA/ATTS domain family)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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