DNA Binding Motif

						

			
Accessions: MGA_EVX1_2 (HumanTF2 1.0)

			
Names: MGA_EVX1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: rGGTGwTAATkwasrTTA
Weblogo: 
PSSM: P0      A      C      G      T
01   1838    106   1074    488      r
02    296      4   1838      1      G
03      0      8   1838      0      G
04     96     18      0   1838      T
05      0      0   1838      1      G
06    767    159    219    692      w
07      1      3     58   1838      T
08   1838      0      0     39      A
09   1838      1     67      7      A
10     57      0     18   1838      T
11      0     18   1143    694      k
12    995    165    324    843      w
13   1146    377     71    244      a
14     97   1169    463    108      s
15    804    133    657    244      r
16    133      2     96   1607      T
17    183     66      0   1838      T
18   1363      2     96    377      A
Type: Heterodimer
Binding TFs: EVX1_TF1 / EVX1_TF2 (Homeobox domain)
MGA_TF1 (T-box)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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