DNA Binding Motif

Accessions: MGA_DLX3_2 (HumanTF2 1.0)
Names: MGA_DLX3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: yvATTAarGGTGtGAr
Weblogo:
PSSM: P0 A C G T
01 1601 9215 2190 6725 y
02 4005 4676 5770 1489 v
03 15940 1082 4784 1343 A
04 0 77 1 15940 T
05 61 2417 182 15940 T
06 15940 493 2144 2870 A
07 6449 2970 3624 2898 a
08 9688 761 6252 2798 r
09 1422 982 15940 1400 G
10 0 1701 15940 156 G
11 0 1188 0 15940 T
12 1 1 15940 0 G
13 4838 2540 598 15940 t
14 241 1797 15940 2278 G
15 15940 59 3883 604 A
16 8576 810 4103 2451 r
Type: Heterodimer
Binding TFs: DLX3_TF2 (Homeobox domain)
MGA_TF1 (T-box)
DLX3_Crystal (Homeobox domain)
DLX3_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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